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Calling all business dreamers!!! We're expanding! If you've ever wanted to join our team, or know someone who would be a great addition, please share with them the latest for our Business Development Consultant position, now global...! For full disclaimers and all information, please see: W. O. LittleSr Global Investments Group https://linktr.ee/realestateinvestor1   Real estateAndy Dean Photography/ShutterstockOwning real estate has historically been one of the most effective ways to both hedge against inflation and earn a passive income. And these days, you don’t need to be a landlord to do it. There are plenty of publicly traded real estate investment trusts that provide generous cash distributions to investors. These companies own income-producing real estate, collect rent from tenants, and then pass the money to shareholders in the form of regular dividends. Realty Income, for instance, has been acquiring and managing commercial properties for over five decades. It earns rental revenue from long-term, net lease agreements and pays monthly dividends to investors. You can look outside of the stock market, too. For instance, some popular investing services let you lock in a steady rental income stream by investing in premium commercial real estate properties — from R&D campuses in San Jose to industrial e-commerce warehouses in Baltimore. EnergyThaiview/ShutterstockOne of the surest signs of surging inflation is in the commodities rally we saw earlier this year. In fact, commodity prices are commonly believed to be a leading indicator of inflation. So it shouldn’t come as a surprise that oil — the most traded commodity in the world — is also on Kiyosaki’s list. The price of crude oil has slipped over the past month, but is still up more than 40% year to date. As you’d expect, strong oil prices benefit oil producers. So far this year, investors have enjoyed outsized returns from names like Chevron (40%), Exxon Mobil (51%), and ConocoPhillips (84%). That said, investing in commodities is a particularly volatile undertaking. If you’d rather invest in something without the extreme ups and downs of stocks, cryptos and commodities, take a look at a few under-the-radar alternative assets. Traditionally, investing in things like exotic vehicles or litigation finance or even marine finance have only been options for the ultra rich, like Kiyosaki. But with the help of new platforms, these kinds of opportunities are now available to retail investors, too. Bathrooms Kitchens Wood Fences Wellness 
NutraBurst helps to detoxify your system and maintain a healthy balance. Eighteen amino acids ensure your body is performing to the best of its ability. NutraBurst works in tandem with enzymes necessary for proper digestion and absorption of the foods you eat. Iaso® Nutraburst plus is more than a regular daily supplement. Total Life Changes’ unique formula provides a broad spectrum of supplements enhanced by the Coenzyme Q10 (CoQ10). One bottle provides thirty-two (sixteen fluid ounce | 470ml) servings. WHY IASO NUTRABURST PLUS IS POPULARHealth experts state that our cells use this coenzyme to produce the energy it needs for cell growth and maintenance. Nutraburst Plus provides a wide array of supplements that include: 72 minerals | 10 Vitamins | 22 Phytonutrients | 19 Amino Acids | 13 Whole Food Greens | 12 Herbs. Therefore, this combo adds up to 148 reasons to start using Iaso Nutraburst plus! Total Life Changes formula delivers up to five times the absorption of nutrients as compared to conventional tablets. Not to mention the fact that Nutraburst Plus is much more economical than if you were to purchase each vitamin separate pills or supplements. IMPORTANT INGREDIENTSCOQ10The CoQ10 provided by Iaso® Nutraburst plus helps to ensure our bodies have optimal amounts of this Coenzyme and is working at peak efficiency. It also functions as an antioxidant which protects our body from damage caused by harmful molecules. MULTI-VITAMIN BLENDIaso® Nutraburst Plus contains thirteen important elements including Ginseng, Grapeseed Extract, Green Tea Extract, and Kelp. Kelp contains high amounts of iodine, potassium, magnesium, calcium, and iron. It also provides antioxidants, phytonutrients, and omega-3 fats. AMINO ACIDSOur formula includes the eight essential amino acids as well as L-Arginine, Aspartic Acid, Cysteine, Glycine, and Glutamic Acid. Cysteine aids in the formation of healthy skin, hair, bones, and connective tissues. ECONOMICALIaso® Nutra Burst+ is more economical to purchase than the same number of individual nutrients provided by different bottles or capsules. Iaso® Nutra Burst+ is easier to ingest than difficult-to-swallow pills and tablets. These forms of vitamin delivery are limited to 22% or less of the ingredients. NUTRABURST PLUS IS SAFE FOR THE ENTIRE FAMILYA tablespoon-serving of Iaso® Nutra Burst+ liquid vitamin supplement meets or exceeds the recommended daily consumption of vitamins and essential nutrients. The formula is safe for use by the entire family. 6 Important Facts About Liquid Multivitamins1) A Full Spectrum of Essential Nutrients It has been proven that liquid delivery systems are a scientifically sound way to deliver essential and beneficial nutrients in convenient liquid dose. 2) You Can Enjoy The Benefits of Immediate Absorption The good news it that liquid vitamins and minerals are available for immediate absorption… Unlike pills or tablets that have to be dissolved first. 3) The Best Most Optimal Nutrient Quantities and Ratios are packed in. Each of these vitamins and minerals works together 4) Economical Liquid vitamins are very economical to purchase. Much more so than the same number of individual nutrients in different pills or tables 5) Easy to Ingest Liquid vitamins are so much easier to ingest than those difficult to swallow bulky pills and tablets 6) Enhanced Absorption Liquid multivitamins may have greater absorption than pills and tablets [av_hr class=’short’ height=’50’ shadow=’no-shadow’ position=’center’ custom_border=’av-border-thin’ custom_width=’50px’ custom_border_color=” custom_margin_top=’30px’ custom_margin_bottom=’30px’ icon_select=’yes’ custom_icon_color=” icon=’ue808′ font=’entypo-fontello’ admin_preview_bg=” av_uid=’av-b3p6a’] More on the reported benefits of CoQ10:
Watch Slideshow Medically reviewed by Meera Mohan, M.D. Article written by Heather Lapidus Glassner
When oncologists diagnose people with multiple myeloma, they assign a stage to the condition. Knowing the stage of myeloma allows doctors to better predict how the cancer is most likely to progress and determine which treatment options will be most effective. Multiple myeloma stages can be confusing. Some doctors regard related precancerous conditions, such as monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM), as early, asymptomatic stages of multiple myeloma. Some people with multiple myeloma have questions about whether their cancer will be assigned a new stage if it relapses, or whether staging is the main factor in deciding which treatment will be recommended. “Staging is very different for myeloma,” wrote one MyMyelomaTeam member. “It’s not based on what needs to be done … it’s based on how much of your body is affected.” Another wrote, “Myeloma staging has such different rules — it is tough to learn everything.” To address some of the confusion around this topic, MyMyelomaTeam invited Dr. Meera Mohan to discuss staging in myeloma. Dr. Mohan is a hematologist and oncologist with Froedtert & the Medical College of Wisconsin, where she also serves on the myeloma faculty. What diagnostic procedures do oncologists use to determine the stage in a case of myeloma?Typically, when we have a new patient, we order blood work to assess:
A bone marrow examination is another standard procedure for newly diagnosed myeloma. After analyzing the bone marrow aspirate, we perform a cytogenetic study, which helps us get a snapshot of the biology of the cancer. And, if possible, we always try to incorporate imaging techniques, like a positron emission tomography (PET) computed tomography (CT) scan, and ideally magnetic resonance imaging (MRI) for newly diagnosed multiple myeloma patients. Which stage are most people in when they begin to have symptoms that would lead to a myeloma diagnosis?Stage 3 is rare as compared to stages 1 and 2 — the prevalence of stage 3 is significantly lower. So we see less stage 3, thankfully, compared to stage 1 and stage 2. Does the stage of myeloma indicate the survival prognosis?Yes, the stage does correlate with the survival prognosis — the higher the stage, the poorer the outcome. The five-year survival outcome in patients with R-ISS stage 1 myeloma is about 82 percent. Five-year survival in stage two is 62 percent, and five-year survival for stage 3 is 40 percent. What are the earliest clues that someone might have myeloma? Some MyMyelomaTeam members say they had a bone fracture, while others had no symptoms at all.Often, patients go for an annual physical examination, and they get routine blood work including a basic metabolic panel. A lot of patients get diagnosed in an asymptomatic setting, where the primary care physician notes an elevated level of protein in the blood. Bone disease is very common in multiple myeloma patients. About 80 percent to 85 percent of patients tend to have bone disease. This can lead to a pathological fracture, which means the bones can fracture even without trauma. They could have lesions in the bone, which we call lytic lesions. The myeloma cells tend to erode the bone and cause lytic lesions, which could be incidentally found on an X-ray. They could also have various symptoms like aches and pains, or maybe they are just not generally feeling well. But typically, symptoms such as weight loss or night sweats are much more prominent when you have a lot of tumor burden. They're not very common in the earlier stages of the disease. Are treatment options based mainly on the stage of myeloma? Or are there other factors that play a role in which treatment options doctors recommend?The standard approach for a newly diagnosed myeloma patient involves three stages. What we do first is induction chemotherapy. The goal of that initial stage of the disease treatment is to bring down the tumor burden. The next stage is stem cell transplantation. The whole idea is that the transplantation is supposed to induce a deeper response. And then we have what we call maintenance therapy — the goal is to eradicate any tumor that is left in the body after they undergo a stem cell transplantation. We know from the data available that patients with higher stage and higher risk disease do not have the same outcome as patients with lower stage or standard risk disease. So in the former, we try to treat patients with more effective treatment regimens, such as those including the newer monoclonal antibody daratumumab. Determining the stage at diagnosis is one way to stratify risk in the patients at diagnosis, but in reality, risk assessment is more dynamic throughout the disease course. How long does maintenance therapy typically last?We have emerging data that now supports maintenance till evidence of disease progression, also referred to as relapse. The goal of maintenance therapy is to make sure that the patient has no detectable myeloma cells in the body, which we assess via bone marrow aspiration analysis. But in the typical scenario, duration of maintenance therapy should be balanced out with the side effects of the treatment and how well it’s tolerated. If patients are having trouble tolerating a treatment, they should have a discussion with their oncologist and see if there is any benefit to prolonging the maintenance therapy. Is it possible to go into remission following effective treatment?The majority of patients go into some level of remission after treatment. In advanced myeloma, the challenge is to maintain remission long term. Nevertheless, with the advances, we have a subset of patients who go into long-term remission, which is the ideal scenario. If someone with myeloma goes into remission and then relapses, how is the relapsed myeloma staged?The staging for myeloma is done at diagnosis. So, once the patient has a relapse, we run lab testing, we check kidney function and the level of calcium, and we assess further using PET-CT or magnetic resonance imaging. This gives us a better idea of the disease biology, and all the tests help us make decisions for future treatment. But the stage is assigned at diagnosis. Then if a patient relapses, which the majority do, we consider any relapses to be a higher risk, but we don’t typically change the stage from what existed at the time of diagnosis. What’s the most important thing for people with myeloma to know about the disease stages?The highest stage leads to the poorest outcomes. So, when you have the highest stage disease, your oncologist might suggest alternative treatments or clinical trials, with the hopes of inducing remission. Talk With Others Who UnderstandMyMyelomaTeam is the social network for people with multiple myeloma and their loved ones. On MyMyelomaTeam, more than 12,500 members come together to ask questions, give advice, and share their stories with others who understand life with myeloma. Are you confused about your myeloma stage? Share your experience in the comments below, or start a conversation by posting on your Activities page. |
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January 2023
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